Gibbs, Achane lead Week 5 fantasy football running back rankings

Detroit Lions running back Jahmyr Gibbs leads my Week 5 fantasy football running back rankings. File Photo by David Tulis/UPI
Detroit Lions running back Jahmyr Gibbs leads my Week 5 fantasy football running back rankings. File Photo by David Tulis/UPI

MIAMI, Oct. 1 (UPI) — Jahmyr Gibbs and De’Von Achane lead my Top-50 fantasy football running back rankings for Week 5 of the 2025 season.

Jonathan Taylor, Saquon Barkley and Omarion Hampton join Gibbs and Achane inside my Top 5. James Cook, Ashton Jeanty, Derrick Henry, Travis Etienne and Javonte Williams are my other Top-10 options.

My Top 20 quarterback and Top-50 wide receiver rankings for Week 5 can be found here. My waiver-wire and free agent targets for Week 5 are available here.

All of my positional rankings will be updated until Week 5 kickoffs. Players also will be moved out of or adjusted within the rankings based on injuries.

Be sure to monitor your lineups for injury developments. Players from the Atlanta Falcons, Chicago Bears, Green Bay Packers and Pittsburgh Steelers, who are on bye, should not be in starting lineups. San Francisco 49ers and Los Angeles Rams running backs, who played Thursday, were removed from my rankings.

Miami Dolphins running back De'Von Achane (C) is an elite fantasy football RB1. File Photo by Kevin M. Cox/UPI
Miami Dolphins running back De’Von Achane (C) is an elite fantasy football RB1. File Photo by Kevin M. Cox/UPI

Week 5 running back rankings

1. Jahmyr Gibbs, Detroit Lions at CIN

Minnesota Vikings running back Jordan Mason (L) can stay in lineups as a fantasy football RB2. File Photo by Mark Black/UPI
Minnesota Vikings running back Jordan Mason (L) can stay in lineups as a fantasy football RB2. File Photo by Mark Black/UPI

2. De’Von Achane, Miami Dolphins at CAR

3. Jonathan Taylor, Indianapolis Colts vs. LV

San Francisco 49ers running back Christian McCaffrey is among my Top 5 fantasy football plays for Week 5. File Photo by Terry Schmitt/UPI
San Francisco 49ers running back Christian McCaffrey is among my Top 5 fantasy football plays for Week 5. File Photo by Terry Schmitt/UPI

4. Saquon Barkley, Philadelphia Eagles vs. DEN

5. Omarion Hampton, Los Angeles Chargers vs. WAS

Buffalo Bills running back James Cook is my No. 7 fantasy football running back in Week 5. File Photo by Rena Laverty/UPI
Buffalo Bills running back James Cook is my No. 7 fantasy football running back in Week 5. File Photo by Rena Laverty/UPI

6. James Cook, Buffalo Bills vs. NE

7. Ashton Jeanty, Las Vegas Raiders at IND

8. Derrick Henry, Baltimore Ravens vs. HOU

9. Travis Etienne, Jacksonville Jaguars vs. KC

10. Javonte Williams, Dallas Cowboys at NYJ

11. Quinshon Judkins, Cleveland Browns vs. MIN

12. Breece Hall, New York Jets vs. DAL

13. Cam Skattebo, New York Giants at NO

14. J.K. Dobbins, Denver Broncos at PHI

15. Alvin Kamara, New Orleans Saints vs. NYG

16. Jordan Mason, Minnesota Vikings vs. CLE

17. Chase Brown, Cincinnati Bengals vs. DET

18. David Montgomery, Detroit Lions at CIN

19. Kenneth Walker, Seattle Seahawks vs. TB

20. Woody Marks, Houston Texans at BAL

21. Tony Pollard, Tennessee Titans at ARI

22. Rhamondre Stevenson, New England Patriots at BUF

23. Emari Demercado, Arizona Cardinals vs. TEN

24. R.J. Harvey, Denver Broncos at PHI

25. Rico Dowdle, Carolina Panthers vs. MIA

26. TreVeyon Henderson, New England Patriots at BUF

27. Isiah Pacheco, Kansas City Chiefs at JAX

28. Bucky Irving, Tampa Bay Buccaneers at SEA

29. Zach Charbonnet, Seattle Seahawks vs. TB

30. Rachaad White, Tampa Bay Buccaneers at SEA

31. Michael Carter, Arizona Cardinals vs. TEN

32. Bhayshul Tuten, Jacksonville Jaguars vs. KC

33. Chris Rodriguez, Washington Commanders at LAC

34. Nick Chubb, Houston Texans at BAL

35. Justice Hill, Baltimore Ravens vs. HOU

36. Jacory Croskey-Merritt, Washington Commanders at LAC

37. Kendre Miller, New Orleans Saints vs. NYG

38. Ollie Gordon II, Miami Dolphins at CAR

39. Kareem Hunt, Kansas City Chiefs at JAX

40. Zavier Scott, Minnesota Vikings vs. CLE

41. Isaiah Davis, New York Jets vs. DAL

42. Jerome Ford, Cleveland Browns vs. MIN

43. Devin Singletary, New York Giants at NO

44. Jeremy McNichols, Washington Commanders at LAC

45. Raheem Mostert, Las Vegas Raiders at IND

47. Ty Johnson, Buffalo Bills vs. NE

48. Jaydon Blue, Dallas Cowboys at NYJ

49. Brashard Smith, Kansas City Chiefs at JAX

50. Antonio Gibson, New England Patriots at BUF

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