Beta-blockers are widely prescribed pharmaceuticals used to manage cardiovascular conditions such as hypertension, arrhythmias, and post-heart attack recovery. Among them, atenolol (ATL) and metoprolol (MTL) are particularly common. Their high chemical stability benefits therapeutic efficacy but also means they degrade slowly, persisting in the environment. Conventional wastewater treatment plants are largely ineffective at removing these compounds, allowing them to enter rivers and lakes, where even low concentrations can exert chronic toxic effects on algae, fish, and other aquatic organisms.