The San Francisco 49ers are traveling in Week 16 for an interconference matchup with the Indianapolis Colts on Monday night at Lucas Oil Stadium.
San Francisco has won four in a row since starting quarterback Brock Purdy returned from the toe injury that cost him eight starts. Their offense will be without second-year wide receiver Ricky Pearsall, who caught six passes for 96 yards last week against the Tennessee Titans. They’ll need to find someone else to make an impact in the passing game alongside George Kittle, Christian McCaffrey and Jauan Jennings.
The Colts are going the opposite direction, losing their last four games after starting the year with an 8-2 record. With Daniel Jones and Anthony Richardson on injured reserve, they’ll give 44-year-old Philip Rivers his second start of the year.
Before these two teams meet on the field on Sunday, we’ve gone through picks from roughly 40 experts from different sites/publications to see who they’re taking in this matchup. Let’s take a look at what they said.
Here are all the top expert picks for 49ers vs. Colts in Week 16:
USA Today Sports
- Jarrett Bell: 49ers
- Nick Brinkerhoff: 49ers
- Chris Bumbaca: 49ers
- Nate Davis: 49ers
- Tyler Dragon: 49ers
- Mike Middlehurst-Schwartz: 49ers
ESPN
- Stephania Bell: 49ers
- Matt Bowen: 49ers
- Mike Clay: Colts
- Jeremy Fowler: Colts
- Dan Graziano: 49ers
- Kalyn Kahler: 49ers
- Pamela Maldonado: 49ers
- Eric Moody: 49ers
- Jason Reid: 49ers
- Lindsey Thiry: 49ers
- Seth Wickersham: 49ers
CBS Sports
- Pete Prisco: 49ers
- Cody Benjamin: 49ers
- Jared Dubin: 49ers
- Ryan Wilson: 49ers
- John Breech: 49ers
- Tyler Sullivan: 49ers
- Dave Richard: 49ers
- Jamey Eisenberg: 49ers
Sports Illustrated
- Conor Orr: 49ers
- Gilberto Manzano: 49ers
- Matt Verderame: 49ers
- John Pluym: 49ers
- Mitch Goldich: 49ers
- Clare Brennan: 49ers
- Iain MacMillan: Colts
- Peter Dewey: 49ers
Bleacher Report
- Gary Davenport: 49ers
- Kris Knox: Colts
- Moe Moton: Colts
- Wes O’Donnell: 49ers
- Brent Sobleski: Colts
- Brad Gagnon: Colts
- Ian Hanford: 49ers
NFL.com
- Ali Bhanpuri: 49ers
- Tom Blair: 49ers
- Brooke Cersosimo: 49ers
- Gennaro Filice: 49ers
- Dan Parr: 49ers
More 49ers: Troubled 49ers WR posts video driving recklessly past Levi’s Stadium
This article originally appeared on Niners Wire: 49ers-Colts: Who do experts think will win SF’s Week 16 game?
